SARS-CoV-2 spike in complex with Multivalent miniprotein inhibitor FUS231-P24 (2RBDs open)
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vogeli B, Kruger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetic A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale Jr M, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D
Sci Transl Med (2022) 14 pp. eabn1252-eabn1252 [ DOI: doi:10.1126/scitranslmed.abn1252 Pubmed: 35412328 ]
- Sars-cov-2 spike in complex with multivalent minibinder fus231-p24 (2rbds open) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor fus231-p24 (Complex from Synthetic construct)
- Sars-cov-2 hexapro spike protein (Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 hexapro spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor fus231-p24 (Protein from Synthetic construct)
SARS-CoV-2 spike in complex with multivalent miniprotein inhibitor FUS231-P24 (3RBDs open)
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vogeli B, Kruger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetic A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale Jr M, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D
Sci Transl Med (2022) 14 pp. eabn1252-eabn1252 [ DOI: doi:10.1126/scitranslmed.abn1252 Pubmed: 35412328 ]
- Multivalent miniprotein inhibitor fus231-p24 (Complex from Synthetic construct)
- Sars-cov-2 hexapro spike protein (Protein from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor fus231-p24 (Protein from Synthetic construct)
- Sars-cov-2 hexapro spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike in complex with multivalent miniprotein inhibitor fus231-p24 (3rbds open) (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike in complex with multivalent miniprotein inhibitor FUS31-G10 (2RBDs open)
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vogeli B, Kruger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetic A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale Jr M, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D
Sci Transl Med (2022) 14 pp. eabn1252-eabn1252 [ DOI: doi:10.1126/scitranslmed.abn1252 Pubmed: 35412328 ]
- Sars-cov-2 spike in complex with multivalent miniprotein inhibitor fus31-g10 (2rbds open) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor fus31-g10 (Protein from Synthetic construct)
- Multivalent miniprotein inhibitor fus31-g10 (Complex from Synthetic construct)
SARS-CoV-2 spike in complex with multivalent miniprotein inhibitor FUS31-G10 (3RBDs open)
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vogeli B, Kruger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetic A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale Jr M, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D
Sci Transl Med (2022) 14 pp. eabn1252-eabn1252 [ DOI: doi:10.1126/scitranslmed.abn1252 Pubmed: 35412328 ]
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike in complex with multivalent miniprotein inhibitor fus31-g10 (3rbds open) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor fus31-g10 (Protein from Synthetic construct)
- Multivalent miniprotein inhibitor fus31-g10 (Complex from Synthetic construct)
SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7uhb
Q-score: 0.366
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vogeli B, Kruger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetic A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale Jr M, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D
Sci Transl Med (2022) 14 pp. eabn1252-eabn1252 [ DOI: doi:10.1126/scitranslmed.abn1252 Pubmed: 35412328 ]
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Ahb2-2gs-sb175 (Complex from Synthetic construct)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Multivalent miniprotein inhibitor ahb2-2gs-sb175 (17 kDa, Protein from synthetic construct)
- Sars-cov-2 spike in complex with ahb2-2gs-sb175 (local refinement of the rbd and ahb2) (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike in complex with AHB2-2GS-SB175
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uhc
Q-score: 0.465
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vogeli B, Kruger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetic A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale Jr M, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D
Sci Transl Med (2022) 14 pp. eabn1252-eabn1252 [ DOI: doi:10.1126/scitranslmed.abn1252 Pubmed: 35412328 ]
- Multivalent miniprotein inhibitor ahb2-2gs-sb175 (Complex from Synthetic construct)
- Sars-cov-2 spike in complex with multivalent minibinder ahb2-2gs-sb175 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 hexapro spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor ahb2-2gs-sb175 (17 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)